AndreaSplendiani

BioPAX-Related Research Interests
My interest in BioPAX is from the user perspective. Back in 2005, I was attracted by this project as it promised a source of pathway information whose level of detail was amenable to qualitative pathway analysis. I then found that BioPAX was more than an exchange language: its commitment to represent distinct "interaction" information in a coherent framework makes the BioPAX a relevant resource in the development of biomedical ontologies and data integration solutions.

It is through BioPAX that I then got interested in the Semantic Web, and I have been participating for some time in the BioPAX-OBO initiative.

I am now, advocating, within BioPAX, the adoption of simple good practices which would benefit data integration projects based on Semantic Web technologies (and not only!). These are summarized here. There are routine operation, such as integration of datasets (BioPAX, GO) for data analysis, which could be drastically simplified by the adoption of these steps: i believe BioPAX went already 95% of the effort, in order to get 50% of results. Small improvement can have now a relevant effect.

Some of the projects I'm currently working on which would benefit from improvement in the "integration" side of BioPAX are Ondex and RDFScape

Contact
andrea DOT splendiani AT bbsrc DOT ac DOT uk

Phone. + 44 (0) 1582 763 133 (ext. 2004)

Current position

 * Senior Bioinformatics Scientist - Data integation at Rothamsted Research (UK)

Work experience

 * Post doc, Medical Informatics, Univesity of Rennes 1 - INSERM U936 (FR)
 * Stagiaire Scientifique, Systems Biology, Institut Pasteur (FR)
 * Research Assistant, University of Milano-Bicocca and Genopolis consortium (IT)

Education

 * PhD Computer Science, University of Milano Bicocca (IT)
 * MSc Information Technology, Politecnico di Milano (IT)

Lab Affiliation
Center for Mathematical and Computational Biology, Biomathematics and Bioinformatics Dept. Rothamsted Research, UK

Publications (BioPAX related)
Andrea Splendiani: Semantic browsing of pathway ontologies and biological networks with RDFScape (working paper). Managing and Mining Genome Information 2005

Andrea Splendiani: RDFScape: Semantic Web meets Systems Biology. BMC Bioinformatics 9(S-4): (2008)

Paolo Romano, Andrea Splendiani: Applications of Semantic Web Methodologies and Techniques to Biology and Bioinformatics. Reasoning Web 2008: 200-239